原料介紹

OptiLut®是100%純天然生物可利用的葉黃素和玉米黃素酯製劑,通過純化過程從萬壽菊花中獲得,無需化學轉化。萬壽菊花是自然界中最豐富的葉黃素來源,研究發現,葉黃素酯製劑比非酯製劑具有更高的生物可利用度,超過61.6%。 葉黃素和玉米黃素是在人血液中發現的兩種主要類胡蘿蔔素,是人眼視網膜中晶狀體和黃斑組織中唯一存在的類胡蘿蔔素,被稱為“黃斑色素”,負責清晰和最佳的視力。

原料功效

 

臨床研究顯示,OptiLut®可

  • 幫助保持健康的視覺功能
     

  • 有助於保護眼睛免受藍光傷害
     

  • 有助於降低年齡相關性黃斑變性(AMD)和白內障的風險
     

  • 有助於改善早期AMD的視覺功能
     

  • 幫助中和自由基
     

  • 降低血漿脂質過氧化和炎性C反應蛋白,降低心血管疾病的風險
     

  • 保護皮膚,避免皮膚過早老化或其他自由基相關的皮膚疾病

原料專利

  • US3,769,170 / 7,105,709 / 7,910,340 – 微生物生產輔酶Q10的方法

  • US6,184,255/CA2263404/CN1091368/EP0956854 – 包含輔酶Q10的藥物組合物

  • US7,145,044/CA2453158/CN101774996 – 使用具有高氧化保護作用的溶劑生產還原型輔酶Q10的方法

臨床文獻

  1. Bowen P.E. et al. 2002. Esterification does not impair lutein bioavailability in humans. J Nutr. Dec; 132(12):3668-73 酯化的葉黃素比未酯化葉黃素的生物利用度高61.6%
     

  2. Marse-Perlman J.A. et al. 2002. The body of evidence to support a protective role for lutein and zeaxanthin in delaying chronic disease. Overview. J Nutr. Mar;132(3):518S-524S. 葉黃素和玉米黃素延緩慢性疾病的保護作用
     

  3. Marse-Perlman J.A. et al. 2001. Lutein and Zeaxanthin in the Diet and Serum and Their Relation to Age-related Maculopathy in the Third National Health and Nutrition Examination Survey. Am J Epidemiol. Mar 1;153(5):424-432. 第三次全國健康營養調查中膳食及血清中葉黃素和玉米黃質與年齡相關黃斑病的關係
     

  4. Roberts R.L. et al. 2009. Lutein and zeaxanthin in eye and skin health. ClinDermatol. Mar-Apr;27(2):195-201. 葉黃素和玉米黃素對眼睛和皮膚的保護作用
     

  5. Bovier. ER et al. 2015. A randomized placebo-controlled study on the effects of lutein and zeaxanthin on visual processing speed in young healthy subjects. Arch Biochem Biophys. Apr 15; 572:54-7. 葉黃素和玉米黃素提高視覺處理速度
     

  6. Hammond. BR et al. 2014. A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glared disability, and chromatic contrast. Invest Ophthalmol Vis Sci. Dec 2;55(12):8583-9. 葉黃素和玉米黃素增加黃斑色素,改善光應力恢復和色彩對比
     

  7. Yao. Y et al. 2013. Lutein supplementation improves visual performance in Chinese drivers: 1-year randomized, double-blind, placebo-controlled study. Nutrition. Jul-Aug; 29(7-8):958-64. 葉黃素補充有益於夜間駕駛和其他在低照度下進行的空間辨別任務
     

  8. Stringham JM et al. 2013. Enhancing performance while avoiding damage: a contribution of macular pigment. Invest Opthalmol Vis Sci. Sep 19;54(9):6298-306. 黃斑色素可以增強視覺性能並保護視網膜免受光損傷
     

  9. Loskutova E et al. 2013. Macular pigment and its contribution to vision. Nutrients. May 29;5(6):1962-9. 補充葉黃素,玉米黃素和消旋玉米黃素可增加黃斑色素並增強患病和未患病眼睛的視覺表現,並可降低AMD發展和/或進展的風險
     

  10. Garcia-Layana, A et al. 2013. Effects of lutein and docosahexaenoic acid supplementation on macular pigment optical density in a randomized controlled trial. Nutrients. Feb 15;5(2):543-51. 葉黃素和DHA補充劑可有效增加黃斑色素光密度,並有助於預防年齡相關性黃斑變性
     

  11. Cui YH et al. 2013. Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies. Am J Clin Nutr. Sep;98:778-786. 葉黃素和玉米黃素的血液水平與年齡相關性白內障的風險呈負相關
     

  12. Huang, YM et al. 2016. Changes following supplementation with lutein and zeaxanthin in retinal function in eyes with early age-related macular degeneration: a randomized, double-blind, placebo-controlled trial. Br J Opthalmol. Mar;99(3):371-5. 補充葉黃素和/或玉米黃素可增加黃斑色素光密度,補充葉黃素可增強早期年齡相關性黃斑變性患者的視網膜敏感性
     

  13. Ma, L et al. 2012. Improvement of retinal function in early age-related macular degeneration after lutein and zeaxanthin supplementation: a randomized, double-masked, placebo-controlled trial. Am J Ophthalmol. Oct;154(4):625-634. 補充葉黃素和玉米黃素可改善早期AMD患者中央視網膜的早期功能異常
     

  14. Richer. SP et al. 2011. Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic, age-related macular degeneration: the Zeaxanthin and Visual Function study (ZVF) FDA IND #78,973. Optometry. Nov;82(11):667-680. 玉米黃素補充劑對患有視覺症狀但具有較低風險的早期萎縮性黃斑變性患者提高了黃斑色素光密度(MPOD)和視覺益處
     

  15. Arnold, C et al. 2013. Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial. JAMA Ophthalmol. May; 131(5):564-72. 補充葉黃素,玉米黃素和ω-3 長鏈多元不飽和脂肪酸顯著改善血漿抗氧化能力,循環黃斑葉黃素水平和黃斑色素的光密度
     

  16. Wang, MX et al. 2013. Lutein supplementation reduces plasma lipid peroxidation and C-reactive protein in healthy nonsmokers. Atherosclerosis Apr;227(2):380-5. 健康非吸煙者補充葉黃素可降低血漿脂質過氧化和C反應蛋白,從而降低心血管疾病的風險
     

  17. Meinke MC et al. 2013. Influence of dietary carotenoids on radical scavenging capacity of the skin and skin lipids. Eur J Pharm Biopharm. Jun;84(2):365-73. 膳食類胡蘿蔔素可以保護皮膚免受活性氧的影響,並且可以避免皮膚過早老化和其他自由基相關的皮膚疾病
     

  18. Palombo P et al. 2007. Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study. Skin Pharmacol PhysioL. 20(4):199-210. 口服/局部施用類胡蘿蔔素葉黃素和玉米黃素對人體皮膚提供抗氧化保護作用
     

  19. Connolly EE et al. 2011. Supplementation with all three macular carotenoids: response, stability, and safety. Invest Ophthalmol Vis Sci. Nov 29;52(12):9207-9217. 病理學分析顯示服用葉黃素,玉米黃素和消旋玉米黃素增加中心黃斑色素光密度,並且沒有不利的臨床意義
     

  20. Chew et al. 2014. Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progress: AREDS2 report No. 3. JAMA Ophthalmol. 132(2):142-9. 有關年齡相關性眼病研究(AREDS2)和其他研究的有益和不利影響的證據總體表明,在AREDS型補充劑中,葉黃素/玉米黃素可能比β-胡蘿蔔素更合適

OptiLut®是NutriScience Innovations, LLC的註冊商標

​* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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